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Rimonabant
Rimonabant is the generic version of Acomplia. It is The new weight loss medication breakthrough from Sanofi-Aventis, exceeding Phentermine in it??™s ability to help you lose the weight! It is a CB1 cannabinoid receptor antagonist ,and Its main avenue of effect is reduction in appetite. Rimonabant acts by obstructing the receptors, which control the food intake and energy expenditure - Thus resulting in reduced appetite. Rimonabant also has an added characteristic effect as a smoking cessation aid.
What is Rimonabant used for?
- Rimonabant is used complementary to diet and exercise to treat obese or overweight patients who suffer from Type 2 diabetes and abnormal levels of fat in the blood.
- Sanofi argues that Rimonabant can also prevent the risk of cardiovascular disease.
- Patients with large waist circumference (102 cm in men and 88 cm in women) will mostly benefit from taking the drug.
How Taken
Rimonabant should be taken once a day, before breakfast. The normally recommended Rimonabant dosage is 20mg which should be swallowed with a full glass of water.
How Rimonabant work
Rimonabant have an innovative way of work. Rimonabant block "hunger" receptors in our bodies. This is receptors that send "hunger" message to the brain. The result of taking Rimonabant is appetite suppression. In case if treatment with Rimonabant combined with exercises and a low calorie diet anyone able to lose weight enough fast. Using Rimonabant together with exercises and diet is safe way that bring the best results.
Precautions
If you are undergoing treatment of ongoing major depressive illness and are also on antidepressants for the same, never take Acomplia. Also Acomplia Rimonabant must not be consumed by patients who have or had in past, suicidal thoughts or depressive disorder. Rimonabant is not suggested in patients with uncontrolled psychiatric illness apart from depression. Always envisage the risk of taking Rimonabant yourself and with your caretakers or relatives before you decide to consume it. And as mentioned above if at anytime you witness any symptoms of depression, stop taking Rimonabant with immediate effect.
Rimonabant Interactions
Rimonabant is metabolized by both CYP3A and amidohydrolase (predominantly hepatic) pathways in vitro. Co-administration of CYP3A4 inhibitors will lead to increased exposure of rimonabant. Co-administration of CYP3A4 inducers is expected to reduce the exposure of rimonabant. Potential for other medicinal products to affect rimonabant: Concomitant administration of ketoconazole (apotent CYP3A4 inhibitor) increased rimonabant AUC by 104% (95% prediction interval: 40% - 197%). A similar increase in exposure is expected with other potent CYP3A4 inhibitors. Caution is advised during concomitant use of ACOMPLIA and potent CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir, telithromycin, clarithromycin, nefazodone). Although concomitant administration of CYP3A4 inducers (e.g. rifampicin, phenytoin, phenobarbital, carbamazepine, St John's wort) has not been studied, it is expected that concomitant administration of potent CYP3A4 inducers may reduce the plasma concentration of rimonabant and may result in loss of efficacy. Co-administration of orlistat, ethanol or lorazepam had no significant effect on the plasma levels of rimonabant. Potential for rimonabant to affect other medicinal products: The in vivo inhibitory effect on CYP2C8 has not been studied.
Rimonabant Diet pills to be store?
Rimonabant Diet pills should be stored at room temperature in a cool and dry place. Keep Rimonabant Diet pills away from the reach of children. Protect Rimonabant Diet pills from heat and moisture.
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